I've also found that both Build and Build & Upload (both on the button bar and under the Visual Micro menu) no longer work since the 12th Nov update (I'm now on the latest extension)

If I right click, Rebuild, on the project name then my project compiles, but doesn't upload.

I can get it to compile and upload using the context menu, Debug->Start new instance, but why would the menu commands stop working?

Arduino IDE 1.6.5, Mega 2560 board.

Hi Tim,

I think something must have changed in relation to the "current StartUp project".

I'm developing a .Net application along side an Arduino library and I've had the .Net app set as the default startup application so the green arrow (F5) would launch that.  However, I was still able to build and upload the Arduino sketches using the Visual Micro tool bar simply by selecting the appropriate sketch, and clicking on the Build or Build&Upload buttons.

I'm not sure if this is/was the right way to use it, but it was very convenient.  Now I have to right click->Set as StartUp Project before I can build/upload - which is a bit of a pain.

The latest release has some changes in this area. 

The Visual Micro build and upload buttons should now work if the code currently being edited is arduino code but the startup project is a windows or other non-arduino project.

++ Might be of interest
As an experiment there is also a new "tools>options>visual micro>Application features>Upload/debug active code" setting that can be enabled which always ignores the startup project if arduino code is open and active for edit. The functionality of this setting might be more obvious when multiple arduino projects are in the same solution and one is the  startup project. In this case the F5/continue shortcut key during debug sessions might be more intuitive with the setting switched on.